The John Wesley Holt Legacy Run is an annual event at St. Luke's Episcopal School in Mobile, Alabama, honoring the memory of John Wesley Holt and supporting a scholarship fund established in his name. The event includes a run and a fun run for both runners and walkers, with awards for top finishers in various age groups. Activities such as inflatables, face painting, food trucks, and a car wash are available, with proceeds benefiting the John Wesley Holt Foundation. The event is held regardless of weather, with entry fees considered donations if canceled.