The Little Patuxent River Run is an endurance race held in Columbia, Maryland, on the Patuxent and Wincopin trails, starting and finishing at the Guilford Pratt Truss Bridge. The event features a course along the Little Patuxent and Middle Patuxent Rivers with relatively tame terrain, making it suitable for beginners and intermediate runners. Registration includes a long sleeve shirt, finisher medal, and knit gloves. Participants can earn additional medals by completing multiple race combinations during the event. The race has a participant cap and typically fills quickly.